A Randomized Controlled Trial to Evaluate the Antimicrobial Effect of Petroleum Ether Extract of Arkadigana for Surgical Site Preparation with special reference to Low Anal Fistula

Abstract

Ayurveda, the ancient Indian medical science, provides extensive guidance on wound management Vrana Chikitsa. Sushruta Samhita, considered the foundational text of Ayurvedic surgery, outlines principles of Purvakarma, Pradhana Karma, and Paschat Karma in operative procedures. Various groups of herbs Ganas described under Dravyasangraha Niyama Adhyaya are indicated for Vrana Shodhana wound cleansing and may be used for skin preparation. Ayurvedic literature also mentions several lotions and chemical formulations later validated as potent antimicrobial agents. Although detailed descriptions of surgical site preparation are not explicitly stated in Sushruta Samhita, this step is implied under Purvakarma and aligns with modern surgical practices. Arkadigana is a unique herbal formulation described in Ayurveda with potent antiseptic, antimicrobial, and antifungal properties. Topical application of Arkadigana is considered safe and beneficial in promoting wound hygiene and reducing microbial contamination. Present study evaluates the antimicrobial effect of petroleum ether extract of Arkadigana for surgical site preparation with special reference to low anal fistula.