AYUSHDHARA is an international peer reviewed Bi-monthly open access journal publishing print and online versions. AYUSHDHARA focused towards the publication of current research work carried out under Ayurveda, Yoga, Unani, Siddha and Homeopathy, Allopathy systems of medicine and Pharmaceutical Sciences. AYUSHDHARA title approved for print version by Office of the Registrar of Newspapers for India, Ministry of Information And Broadcasting, New Delhi (RNI Registration No: TELENG/2014/60297). AYUSHDHARA an emerging academic journal in the field of Ayurveda, Yoga, Unani, Siddha and Homeopathy which deals with all facets of the field of research work conducting various institutes and researches. This journal motive and aim is to create awareness, re-shaping the knowledge already created and challenge the existing theories related to the field of Academic Research in any discipline in AYUSH Systems strive to set the highest standards for superiority in everything we do in content, style and aesthetics of presentation, in editorial performance at every level, in transparency and accessibility to the scientific community and public, and in educational value. The journal aims to publish novel research being conducted and carried out of academic and industry authors, researchers, and readers in a medium customized for the discovery, integration, and application of research. We are inviting professors, researchers, professionals, academicians and research scholars to submit their novel and conjectural ideas in the domain of AYSUH Systems in the shape of (1). Original Research Articles (2). Review articles (3). Book Reviews (4). Short Communications/ Research Letter (5). Case Report (6). Letter to the Editor/Correspondence. Ayurved Samhita & Siddhanta (Ayurvedic Compendia & Basic Principles), Rachana Sharir (Anatomy), Kriya sharir (Physiology), Dravyaguna Vigyan (Materia Medica & Pharmacology), Rasashastra (Ayurvedic Metals & Minerals/Iatrochemistry) Bhaishajya Kalpana (Pharmaceuticals Science), Agadtantra & Vidhi Vaidyaka (Toxicology & Forensic Medicine), Svasthavritta (Preventive, Social Medicine & Yoga), Roganidana & Vikriti Vigyan (Pathology & Diagnostic Procedure), Kayachikitsa (General Medicine), Manovigyan & Manasroga (Psychiatry), Rasayan & Vajikaran (Rejuvenation & Aphrodisia), Panchakarma (Five Bio-cleansing Procedures), Prasuti & Stri Roga (Gynecology & Obstetrics), Kaumarbhritya-Balaroga (Pediatrics), Shalyatantra (General Surgery), Shalakyatantra (Otorhinolaryngology/ENT & Ophthalmology). Research articles on above the subjects using current scientific knowledge viz., Ethnobotany, Phytochemistry, Drug Standardization, Quality control, Good Laboratory Practices (GLP), Pharmacology, Preclinical research, Clinical research, Good Clinical Practices (GCP), Pharmacovigilance. Studies on Literary, Basic and Fundamental research, Preventive and Promotive Healthcare, Local Health Traditions, etc. which provide the leads to the original research are also acceptable. Pharmaceutical Sciences Further, studies on Herbal/Natural products in the area of Pharmaceutical Chemistry, Pharmacognosy and Phytochemistry, Drug delivery systems, Pharmacology, Pharmaceutical analysis, Herbal/Ayurvedic Pharmacy practice, Bioinformatics and Pharmaceutical biosciences.
Skin disorders are one of the major health issues in the present era. It is a multifaceted condition that includes the emotional and social impact on individuals, as it affects the psychological status of a person due to its appearance, severe itching, and disturbance to the daily routine. The prevalence of eczema is more common in rural areas than in urban ones. Eczema is an inflammatory reaction of the skin, characterized by variable itching and soreness, crusting, dryness, erythema, excoriation, exudation, fissuring, hyperpigmentation, lichenification, oozing, scaling, and vesiculation. No satisfactory treatment is available in contemporary medical practice except antihistamines and topical steroids. As it is a common chronic skin condition, it can lead to recurrent infections and poor quality of life if left untreated. The clinical features can be correlated to Vicharchika in Ayurveda, as it is characterized by Kandu, Srava, Pidaka, and Shyava Varna. It has been described under Kshudra Kushthas and is a Rakta Pradoshaja Vikara, involving three Doshas with Kapha predominance. A 36-year-old female patient presented with clinical features of diffuse hyperpigmented skin lesions on both lower limbs, associated with severe itching and a burning sensation for the past six years. The case was diagnosed as Vicharchika. The patient was treated following the principles of Rakta Pradoshaja Vikara (Kustha), i.e., Sroto Shodhana (purification of channels) and Dosha Shamana (pacification of doshas) Chikitsa, resulting in significant improvement in clinical symptoms.
Vicharchika, Eczema, Kshudra Kushthas, Rakta Pradoshaja Vikara
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Literature Review on Pratisaraneeya Kshara in the Management of Arsha (Haemorrhoids) by Acharya Sushruta
Arsha (haemorrhoids) is commonest anorectal disorder affecting a large portion of the population and is characterized by engorgement and prolapse of superior haemorrhoidal venous plexus. In Ayurveda, Arsha has been classified as a Tridoshaja Vyadhi and Acharya Sushruta has placed it among Ashta Mahagada in Sushruta Samhita. In modern science various treatments are used e.g. conservative measures, non-operative procedures and operative procedures. Acharya Sushruta, Father of surgery, was first to describe Kshara in Sushruta Samhita in an elaborated manner. He has described Bhesaja, Kshara, Agni and Shashtra Karma for treatment of Arsha. Among the various treatments described Pratisaraneeya Kshara Karma (alkaline cauterization) is considered as highly effective and minimally invasive para-surgical procedure for the treatment of haemorrhoids. It offers an alternative way to conventional surgery with lesser complications and minimal chance of recurrence. This research article explains and review about Pratisaraneeya Kshara usage in the treatment of Arsha given by Acharya Sushruta.
Kshara, Arsha, Pratisaraneeya Kshara, Ayurveda
Ayurvedic Approach in the Successful Management of Psoriasis
Psoriasis is an autoimmune skin disorder characterized by dry, scaly patches and inflammation, often exacerbated by environmental factors, stress, and local injuries. Ayurveda, addresses psoriasis as a result of Tridosha imbalance, particularly the vitiation of Pitta and Kapha, alongside the involvement of Raktadhatu and Mamsadhatu. The disease is managed through a holistic approach, combining Sodhana (purification therapy) and Shamana (palliative therapy). In this case, a 21-year-old male patient presented with symptoms of scaly, reddish-black patches along with itching and burning on the whole body for one year. After clinical examination and diagnosis of Ekakushtha (psoriasis), a tailored Ayurvedic treatment protocol was implemented, integrating Panchakarma therapies and internal medicines. Key interventions included Deepana (digestive stimulation) with Panchkola Churna along with Takradhara, Snehpana (internal oleation) with Murchchita Goghrita, followed by Vamana Karma (emesis) and Virechana (purgation) followed by Samsarjana Krama. The treatment was complemented by oral medications and oil for local application. Over a period of 90 days, significant clinical improvements were observed, with reduced itching, burning, and scaling, leading to complete recovery. The patient showed no recurrence of symptoms, demonstrating the efficacy of this multimodal Ayurvedic approach. This case highlights the potential of Ayurveda to manage chronic, autoimmune conditions like psoriasis by addressing the root causes of the disease, offering long-term relief and improved quality of life. Further research is needed to validate these findings and explore the broader applicability of Ayurvedic treatments for chronic inflammatory skin diseases.
Ayurveda, Psoriasis, Panchakarma, Vamana, Virechana
A Comprehensive Review of Vidangadi Churna and its Role in Ayurvedic Medicine
Ayurveda, the ancient Indian system of medicine, adopts a holistic perspective on health, emphasizing the balanced integration of body, mind, and spirit. Among its major disciplines, Bhaishajya Kalpana (Ayurvedic pharmaceutics) is concerned with the formulation, preparation, and quality assurance of medicinal products. Within this field, Churna Kalpana refers to herbal formulations in powdered form, which are widely appreciated for their ease of administration, fast absorption, and long shelf life. In Ayurvedic understanding, Krimi Roga encompasses diseases caused by internal and external parasites, often resulting from unclean habits, poor dietary choices, and lifestyle imbalances. To manage such conditions, classical texts recommend Vidangadi Churna- a traditional polyherbal preparation, with Vidanga (Embelia ribes) as its principal component. This formulation includes herbs with Krimighna (antiparasitic), Deepana (digestive stimulant), and Pachana (carminative) properties, aimed at eradicating intestinal parasites, strengthening digestive fire (Agni), and preventing recurrence. By supporting detoxification and enhancing digestive function, Vidangadi Churna showcases the therapeutic potential of Ayurvedic interventions in managing parasitic disorders. Scientific validation and standardization of such classical formulations can enhance their credibility and set the stage for their integration into modern evidence-based healthcare systems.
Ayurveda, Bhaishajya Kalpana, Churna Kalpana, Krimi Roga, Vidangadi Churna, Antiparasitic
Hormonal Axis in Malignancy - From Pathogenesis to Therapeutics: Insights from Modern Oncology and Ayurveda
Hormonal regulation is central to cancer pathogenesis, influencing cell proliferation, apoptosis, angiogenesis, and immune surveillance. Dysregulation of endocrine axes-including hypothalamus-pituitary-gonadal (HPG), hypothalamus pituitary adrenal (HPA), hypothalamus-pituitary-thyroid (HPT), and pituitary–liver axes-drives hormone-sensitive malignancies such as breast, prostate, ovarian, thyroid, and liver cancers. Genetic, lifestyle, and environmental factors further modulate hormonal balance and cancer susceptibility. Ayurvedic principles provide a complementary framework, linking Dosha imbalance, Dhatu dushti, Srotorodha, ama accumulation, and Ojas kshaya to endocrine dysfunction. Therapeutic strategies include modern hormone-targeted agents (selective receptor modulators, aromatase inhibitors, androgen blockers, PI3K/mTOR/CDK4/6 inhibitors) and context-specific Ayurvedic herbs (Ashwagandha, Shatavari, Rasayanas), emphasizing careful monitoring in hormone-sensitive cancers. Integrating modern oncology with Ayurvedic approaches, along with lifestyle modification, may offer holistic strategies for the prevention and management of endocrine-responsive malignancies.
Hormonal axes, Cancer pathogenesis, estrogen receptor, androgen receptor, PI3K/AKT pathway, Dosha imbalance, HPG axis, HPA axis, Hormone-targeted therapy, Ashwagandha, Shatavari, Endocrine-responsive cancers
Addressing Metabolic Dysfunction-Associated Steatohepatitis (Mash) Through Panchakarma: An Evidence-Based Review
Metabolic dysfunction-associated steatohepatitis (MASH, formerly NASH) is an inflammatory progressive liver disease that arises from metabolic dysfunction and hepatic steatosis, carrying risk of fibrosis, cirrhosis, and hepatocellular carcinoma. Lifestyle change is first-line prevention, but complementary approaches such as Ayurvedic Panchakarma, a system of individualized detoxification and rejuvenation therapies are increasingly investigated for prevention and early management of steatotic liver disease. This review synthesizes current understanding of MASH, maps it to Ayurvedic pathogenesis, reviews the putative mechanisms and available clinical/experimental evidence for Panchakarma, and proposes a pragmatic framework for integrating Panchakarma into prevention strategies while highlighting research gaps and safety considerations.
Ayurveda, Metabolic Dysfunction-Associated Steatohepatitis, Panchakarma, Prevention
ADRs & its Reporting for ASU Drugs - Need of an Hour
Due to irrational usage of ASU drugs, Adverse Drug Reactions (ADRs) becoming significant concern for Ayurvedic medicine, and it is essential to understand the causes of ADRs, its consequences and adopt prevention strategies to minimise its adverse effects. In present era, scope of pharmacovigilance increasing day-by-day due to increase in ayurvedic pharmaceutical products in market. In Ayurveda, the principle of drug safety emphasizes on factors like drug interactions (Viruddha Dravya), overdosing (Atimatra Dravya Prayoga), Pathya- Apathya during Oushadha sevana kala and individual patient suitability (Satmya). So, It become essential to understand the causes of ADRs, its consequences and adopt prevention strategies to minimise its adverse effects. Ministry of Ayush also launched Ayush Suraksha portal for reporting of ADRs through online mode. Ayush Suraksha focussed on Ayush medicine for betterment of patient safety. This ADR form filling method will refine clinical practices and minimize the same drug reactions on others.
ADRs, adverse drug reaction, Viruddha Ahara
Daiva as Dravya: Recontextualizing Daivavyapashraya Chikitsa through the Lens of Atharvaveda and Psychodermatology
Daivavyapashraya Chikitsa, one of the three main categories of treatment in Ayurveda, is often perceived as spiritual or religious therapy aimed at alleviating diseases caused by unseen forces (Adrishta). Although this form of therapy has often been ignored as non-rational or non-clinical, a deeper analysis reveals its organized and purposeful nature. Ayurveda is an Upaveda of the Atharvaveda. Atharvaveda, the fourth Veda, is a primary textual source that closely aligns with Ayurvedic philosophy and practices. It presents many Sukta (hymns) that directly address disease, mental imbalance, possession, poison, infertility, and skin afflictions, often prescribing ritual and verbal treatments that mirror Daivavyapashraya practices. Sukta like Kushthanashana Sukta, Kriminashana Sukta, etc., reveal the early integration of Mantra and other disciplines into therapeutic frameworks. By re-evaluating Daivavyapashraya through the Atharvavedic lens, this study highlights its foundation in textual tradition and its relevance as a valid and well-organized healing system. It bridges spiritual, psychological, and somatic domains, making it particularly applicable to the management of psychosomatic and psychodermatological conditions in the present era. This recontextualization encourages the inclusion of Daivavyapashraya in integrative medicine, emphasizing its preventive, promotive, and curative aspects. This review advocates the concept of “Daiva as Dravya,” viewing divine interventions as therapeutic elements rather than abstract metaphysical concepts.
Ayurveda, Daivavyapashraya Chikitsa, Atharvaveda, Mantra Chikitsa, Psychodermatology
Neuro-Muscular Rehabilitation Through Basti and Mamsa Pinda Sweda in Hirayama Disease
Hirayama disease is characterised by juvenile onset of unilateral muscular atrophy of distal upper extremity. The disability originates with impaired functioning of anterior horn cells of the cervical cord. Studies consistently note a loss of the cervical lordosis and compression of the cervical cord by the dural sac in forward flexion. Here is a case report of a 24-year old male with Hirayama disease who had been treated as inpatient. The case was considered as a Vatavyadhi and the treatment protocol applied accordingly with incorporation of treatment of Asthikshaya, Vishwachi and Bahushosha particularly. The treatment included Abhyanga, Seka, Mamsa Pinda Sweda, Mustadi Yapana Basti and Rasayana Oushadhi. Even though the patient condition was irreversible, he was able to regain the functional status after restarting the treatment. The case highlights the improvement in quality of life of the patient after Ayurvedic management.
Dashamoola Kashaya Seka, Mamsa Pinda Sweda, Mustadi Yapana Basti
A Critical Review on Ritucharyam Adhyayam mentioned in Sushruta Samhita
The sixth chapter of the Sushruta Samhita Sutra Sthana is the Ritucharya Adhyaya. Acharya Sushruta clarified that Roga can be avoided before it manifests if one abides by Ritucharya's precepts. Thus, Ritucharya is an Ayurvedic preventive and health-promoting practice that helps people live in harmony with nature and stay healthy throughout time. Sushruta Samhita Sutra Sthana is the source of literature about Ritucharya. In Ritucharya, Acharya Sushruta explains what should be done in each season (Samshodhana kala) to stop illnesses before they start According to him, for Swasthya Rakshana Snehapana and Basti should be conducted in Varsha Ritu to calm Vata dosha, Virechana should be performed in Sharad Ritu to balance Pitta dosha, and Vamana should be performed in Vasanta Ritu to balance Kapha dosha.
Sushruta Samhita, Ritucharya, Samshodhana Kaala, Swasthya Rakshana
Healing Effect of Localized Therapies In Swethapradara
In Ayurveda, leucohrrea is a common issue faced by women of reproductive age, and it is linked to Shweta Pradara, which refers to an excessive vaginal discharge. One type of Striroga that influences the daily lives of women is Swethapradara. Since it is regarded as a symptom of various Stri rogas or Yoni vyapads, Sthanika Chikitsa, as outlined in Striroga, is highly relevant to Swetha Pradara. Our Acharyas have described various forms of Sthanika Chikitsa across numerous Ayurvedic texts. These methods include Uttara Basti, Yoni Parisheka, Yoni Swedana, Yoni Pichu, Yoni Poorana, Yoni Dhavana, Yoni Dhoopana, Yoni Lepana, and Yoni Varti. In Sthanika Chikitsa, medications are administered intravaginally through various forms of therapies. The administration of medication via the vaginal route is the most preferred and accepted approach for addressing various reproductive health concerns. Modern treatments such as vaginal douching, suppositories, tampons, vaginal painting, and cauterization are seen as adaptations of Sthanika Chikitsa, as outlined in Ayurveda. Each method of Sthanika Chikitsa holds its own importance and shows significant effectiveness when applied with proper indications and stringent aseptic practices, necessitating meticulous care. Swetha Pradara is one condition where Sthanika Chikitsa has shown remarkable success in mitigating the disorder. This study offers a comprehensive examination of the localized therapies, or Sthanika Chikitsa, as put forward by Ayurveda experts. The methods of Sthanika Chikitsa are affordable, safe, and efficient, with no known adverse effects reported.
Sthanika Chikitsa, Swetha pradara, Localized, therapies, leucorrhoea
Hansodhak: An Ayurvedic Perspective of Water Purification in Sharad Ritu with Modern Correlation
Ayurvedic texts emphasize the necessity of pure water for health and disease prevention. Contaminated water (Dushta Jala) has been identified as a major cause of illnesses, especially in the post-monsoon period. The concept of Hansodhak Jala- naturally purified water- describes water acquiring cleansing and therapeutic properties when exposed to Surya (sunlight), Chandra (moonlight), and Agastya Nakshatra (Canopus star). This practice holds particular relevance in Sharad Ritu, a season linked to aggravated Pitta dosha and frequent waterborne diseases. The present study examines classical references to Hansodhak Jala and assesses their symbolic and practical significance. The traditional view is correlated with modern scientific methods of purification, including solar disinfection (SODIS), photodynamic treatment, and seasonal epidemiology. Findings suggest that Hansodhak Jala represents a natural, eco-friendly, and community-based strategy for ensuring water safety. The study concludes that Hansodhak Jala bridges ancient Ayurvedic wisdom with contemporary public health practices, underscoring the enduring relevance of traditional approaches in securing safe drinking water.
Hansodhak Jala, Dushta Jala, Agastya Nakshatra, Sharad Ritu, Water Purification, Solar Disinfection
Ayurvedic Management of Papular Dermatosis
Papular dermatoses are a group of skin disorders characterized by multiple small, raised papules, among which lichen nitidus is one of the uncommon variants. It is a rare, chronic inflammatory condition of the skin, mostly in children and young adults. It may cause considerable discomfort due to pruritus and may necessitate treatment for cosmetic or symptomatic relief. This case study explores the diagnosis and Ayurvedic management of a 17-year-old male patient with papular lesions on the scalp, for whom a probable diagnosis of lichen nitidus was considered based on clinical features. Management incorporated a Dosha-based approach along with Ayurvedic principles of Kushta Roga, using oral formulations and topical applications. The patient experienced symptomatic improvement, with reduced itching and complete resolution of lesions. This case highlights the potential role of Ayurvedic management in papular dermatoses and emphasizes the need for further exploration of Ayurvedic principles in their management through well-designed clinical studies.
Papular Dermatosis, Lichen Nitidus, Kushta roga, Kaphadika kushta roga
Therapeutic Potential of Brahmyadi Yoga in the Management of ADHD: A Comprehensive Review
Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorders of childhood, characterised by inattention, impulsivity, and hyperactivity, which significantly affect academic, social, and emotional functioning. The etiology of ADHD is multifactorial, involving an interplay of neurobiological, environmental, and genetic determinants. If left untreated, ADHD can hampers learning ability, self-regulation, and behavioural development, leading to long-term challenges in adulthood. Ayurveda provides a comprehensive approach to such cognitive and behavioural disorders. Brahmyadi Yoga, a classical polyherbal formulation, contains Brahmi, Shankhapushpi, Vacha, Kushmanda with Kushta and Madhu which are well known for their Medhya Rasayana (nootropic and cognitive-enhancing) properties. Its bioactive phytoconstituents exert neuroprotective, adaptogenic, and nootropic effects, supporting brain plasticity, neurotransmitter modulation, and impulse regulation. By reducing hyperactivity, improving concentration, and enhancing cognitive functions, Brahmyadi Yoga offers a safe and holistic therapeutic option for managing ADHD in children.
Attention Deficit Hyperactivity Disorder (ADHD), Brahmyadi Yoga, Medhya Rasayana
Effect of Yonidhawan and Yoni Pichu in Karnini Yonivyapad w.s.r to Cervical Erosion
A cervical erosion is a condition in which the squamous covering of the vaginal aspect of the cervix is replaced by columnar epithelium which is continuous with that lining the endocervix. It is not an ulcer. Cervical erosion is typically manifested by heavy vaginal discharge (watery or whitish), contact bleeding and sometimes it may be associated with cervicitis. Its treatment is based on the principle of destruction of the columnar epithelium to be followed by its healing by the squamous epithelium. In Ayurvedic classics almost all the gynecological disorders come under the term Yonivyapad. It is best correlated with Karnini yonivyapad due to similarities in etiopathogenesis, clinical features and complications. This lesion is non-cancerous, but if not managed appropriately, it can contribute to infertility and may occasionally progress towards malignancy. In Ayurveda, Krnini yonivyapad can be treated with different treatment modalities like Yoni dhawana, Yoni pichu, Yoni varti, Ksharakarma, Agnikarma and the oral administration of the ayurvedic drugs. In this case study, patient with Karnini yonivyapada is treated with Panchvalkala kwatha yoni prakshalna followed by Jatyadi tailam yoni pichu one time daily for 10 days for consecutive two cycle and oral administration of ayurvedic medicine. The Yoni prakshalana and Yoni pichu in this case has showed the good results in improvement of Karnini yonivyapad.
Karnini yonivyapad, Cervical erosion, Panchavalkal kwath, Yoniprakshalana, Yonipichu
Ayurvedic Management of Female Infertility Associated with PCOD and Tubal Obstruction
Experience of infertility can place significant emotional and psychological burdens on those going through it. It generally refers to the inability to conceive after a year of regular, unprotected intercourse, or the inability to carry a pregnancy to term. According to the World Health Organization (WHO), approximately 17.5% of the adult population worldwide equivalent to one in six individuals experience infertility during their lifetime and there are various reasons behind the infertility. In Ayurveda an umbrella term Vandhyatwa is used to denote any kind of infertility and four factors such as Ritu, Ambu, Kshetra, Beeja are responsible for the reproduction. Any defect on the single factor hinders the fertility. In this case study a 26 year old female, married for three years, presented with infertility attributed to PCOD with left para ovarian cyst (Beeja dusti) and bilateral tubal obstruction (Kshertaj dusti), provide with Shodana and Shaman Chikitsa including Anuvasana Basti with Dashmool Taila and Asthapana with Dashmool kwatha in the form of Yoga Basti and Uttar Basti with Ksheerbala taila. Following two months of this Ayurvedic treatment regimen, the patient successfully conceived, demonstrating a significant improvement in reproductive health. This case underscores the potential of Ayurvedic treatments, particularly through the application of Sodhana and Shamana Chikitsa, in managing infertility related to PCOD and tubal obstruction.
Infertility, PCOD, Sodhana Chikitsa, Shamana Chikista, Uttar Basti
Healing from the Ground Up: Ayurvedic Case Study on Vipadika
Skin diseases have been widely described in Ayurveda under the broad term “Kushta.” Among these, Vipadika is classified as a Kshudra Kushta (minor skin disorder) and is primarily associated with an imbalance of Vata and Kapha doshas. It is characterized by painful cracks, excessive dryness, roughness, itching and occasional bleeding, mainly affecting the palms and soles. Contemporary treatment options often lead to temporary relief with frequent recurrence, leading patients to seek alternative therapies. The present case report aims to assess the therapeutic efficacy of Ayurvedic management in treating Vipadika. A 51-year-old male presented with fissures, dryness, roughness in both sole and pain, itching; diagnosed as Vipadika. The treatment approach exclusively involved Shamana Chikitsa, including the oral administration of Avapidak snehpan, Arogyavardhini vati, Gokshuradi gugul, Kaishor gugul, Phalatrikadi kadha, combination of Yashtimadhu guduchi shunthi haritaki churna. Topical care was provided by washing the affected area with lukewarm water and application of Kailas jivan lotion. Pathya-Apathya regarding diet and lifestyle also suggested. The patient's response was assessed over ten weeks, with post treatment follow-up of four weeks to assess symptom improvement and patient-reported outcomes. This case highlights the potential effectiveness of Ayurvedic interventions in managing Vipadika, offering a promising alternative or complementary approach for conditions resembling palmoplantar psoriasis, especially in cases prone to relapse.
Ayurved, Kshudra Kustha, vipadika, Skin Disease, Shamana Chikitsa, Avapidak ghreetpana
Psychological Dimensions of Sexual Weakness: A Comprehensive Review
Ayurveda provides direction and inspiration for leading a healthy and balanced life. In today’s fast-paced life, experiencing stress is common, and this stress leads to many kinds of diseases in the human body. According to Dr CB Pert Neuropeptides and their receptors form a biochemical network linking the mind and body, acting as emotion molecules that carry emotional information throughout the body, and affecting both physical and mental health." In a rural survey conducted in Haryana (North India), it was found that 81% of adult men reported sexual health issues. The most frequent was self-perceived semen defect (64.4%), followed by loss of libido (21%), guilt about masturbation (20.8%), erectile dysfunction (ED) (5%), and premature ejaculation (PE) (4.6%). Sexual health and psychological well-being are closely linked, each influencing the other in significant ways. Mental health challenges such as depression, anxiety, low confidence, and ongoing stress can decrease sexual desire and cause issues like erectile dysfunction or premature ejaculation. This happens because psychological distress alters the brain’s chemistry, which can disrupt normal patterns of arousal and sexual function. Conversely, ongoing sexual difficulties may create emotional strain, leading to feelings such as guilt, frustration, performance anxiety, or tension within relationships. These reactions can intensify the original sexual health concerns, creating a cycle where psychological and physical factors reinforce each other. Ayurveda also recognizes this connection, describing how emotional states and mental well-being contribute to or result from sexual vitality. Ayurvedic approaches emphasize the importance of balancing the mind and body, addressing both psychological and physiological elements to improve sexual health.
Ayurveda, Psychological issue, Loss of libido, Vajikarana
A Comprehensive Ayurvedic Approach to Multisystem Disease
Chronic liver disease is a progressive condition that may result from multiple etiologies including alcohol abuse, recurrent jaundice and metabolic disorders. Management is challenging in patients with multiple co-morbidities. Decompensated liver disease also knows as de-compensated cirrhosis when the liver damaged can no longer compensate for its impaired functions. This stage signifies a severe decline in liver functions and can be life threatening if not addressed often requires liver transplant. As a complication it leads to serious complications like hepatorenal syndrome. Conventional medicine primarily focuses on disease specific pharmacological control there by limiting the scope for holistic recovery. This case repost presents a 55yr old male parent with a complex history of decompensated liver disease chronic kidney disease, type 2 diabetes mellites, hypertension and cardio vascular disease, cerebro vascular accident. An integrated approach using classical Ayurvedic management and panchakarma procedures was adopted over 12 months of outpatient treatment, the patient showed marked improvement is liver function, glycemic control, renal markers and blood pressure regulations without hospitalization. This case highlights the potentials of Ayurvedic intervention is Chronic multi system condition where standard treatment plateau. In Ayurveda, CKD can be correlated with various forms of Mootraghata, a Tridoshaja condition where urine formation is impaired due to intrinsic and extrinsic factors such as suppression of natural urges, intake of Ruksha Padartha, Tikshna Aushadha, and obesity-related Medovaha Srotodushti. The pathology primarily involves Vata Prakopa in the Basti region. Considering the similarity in symptoms, Ayurvedic management of CKD emphasizes Sthoulyahara (anti-obesity), Mootrala, and Mootraghatahara approaches along with Shotha Vyadhi Chikitsa. This case study illustrates a safe and effective Ayurvedic alternative for CKD management.
Decompensated liver disease, Arogyavardini Vati, Punarnava Mandoora, Chronic kidney Disease
Managing Fever Through Ayurvedic Therapeutic Diet
Fever is a common symptom in many diseases and infections. People frequently resort to antipyretics and thereby suppress their immune system resulting in chronic low-grade inflammation in the long run. Body has the power to heal itself provided we are giving adequate support through therapeutic diet and fluid. According to Ayurveda Agni is deranged in Jwara which is responsible for all the associated symptoms. We can correct this Agni through therapeutic diet. In Ayurvedic text various Acharyas described countless therapeutic dietary preparations in the context of Jwara which have antipyretic effect, immunomodulatory effect and act by correcting the Agni. Such preparations mentioned in the classical textbooks of Ashtanga Sangraha, Sharngadhara Samhitha, Chakradutta, Chikitsamanjari, Bhavaprakasham and articles have been identified and listed in this literature review. People are reluctant to use such Ayurvedic therapeutic diet due to complexity in the preparation of these recipes and the limited availability of certain drugs. More clinical research should be done in the field of Ayurvedic nutraceuticals to overcome these limitations.
Jwara, Fever, Nutraceuticals, Therapeutic diet.
Exploring the Dynamics of Doshas a Research-Based Review on Kriya Sharir
The concept of Doshas- Vata, Pitta, and Kapha- is fundamental to Ayurvedic medicine and is vital for maintaining the balance and overall health of the human body. In Ayurvedic philosophy, these three Doshas influence not only physical functions but also mental and emotional health. The balance between these doshas affects various health aspects, including metabolic activities, immune response, mental clarity, and emotional stability. Kriya Sharir, which focuses on the study of bodily functions and physiological systems, provides insights into the interaction of Doshas, their functioning within the body, and the implications of any imbalances that may arise. This review examines the complex relationships between Doshas, their regulatory roles in bodily systems, their effects on disease development, and the clinical relevance of maintaining Dosha equilibrium. By integrating ancient Ayurvedic texts with modern scientific findings, it explores the influence of Doshas on various physiological activities, including digestion, metabolism, elimination, circulation, and neurological functions. Furthermore, the paper investigates how imbalances in Doshas can lead to the onset of diseases and disorders, underscoring the holistic approach of Ayurvedic treatments designed to restore balance. Through a thorough analysis of relevant classical and contemporary literature, this paper emphasizes the significance of understanding doshas within Kriya Sharir as a foundation for personalized healthcare. It also aims to present evidence-based insights into Ayurvedic perceptions of health and disease, thereby enhancing appreciation for dosha dynamics and their relevance in modern health practices. Additionally, the research highlights potential areas for future studies that bridge traditional Ayurvedic knowledge with contemporary medical science, advocating for integrative strategies in health management and disease treatment.
Doshas, Kriya Sharir, Vata, Pitta, Kapha, Ayurveda, Disease Prevention, Personalized Medicine, Health Optimization
A Case Study on Ayurvedic Management of PCOS-Induced Infertility with Successful Conception
Polycystic Ovarian Syndrome (PCOS) is a major cause of infertility in women of reproductive age, often linked to lifestyle and metabolic disturbances. Ovulatory dysfunction accounts for nearly 30–40% of infertility cases. Diagnosis is typically based on at least two of the following: clinical/biochemical hyperandrogenism, oligo/anovulation, and polycystic ovarian morphology on ultrasonography (USG). Objective: To assess the effectiveness of Ayurvedic management in a case of secondary infertility associated with PCOS, focusing on restoration of ovulatory function and achievement of natural conception. Case Description: A 27-year-old female presented to the Prasuti Tantra and Stri-Roga Outpatient Department, National Institute of Ayurveda, Jaipur, on 11 June 2024, with secondary infertility of 1.5 years. Routine clinical, physical, and laboratory findings were within normal limits, except for USG evidence of bilateral polycystic ovaries. Intervention: A personalized Ayurvedic regimen was initiated, aimed at correcting hormonal imbalance, promoting ovulation, and enhancing reproductive health. The treatment plan included dietary regulation, lifestyle modification, and classical Ayurvedic formulations tailored to the patient’s condition. Outcome: After ten months of therapy, the patient reported a missed menstrual cycle. A urine pregnancy test on 7 March 2025 confirmed conception. Conclusion: This case highlights the potential role of Ayurvedic interventions in managing PCOS-related infertility. The observed outcome suggests that integrative, individualized treatment approaches may effectively restore ovulatory function and support natural conception, offering a promising alternative for women with reproductive disorders linked to ovulatory dysfunction.
Polycystic Ovarian Syndrome, Secondary infertility, Ovulatory dysfunction, Ayurvedic management, Hormonal imbalance
Comparative Quantitative Assay of Apigenin and Luteoline Study of Different Market Samples of Bharangi (Clerodendrum Serratum Linn) w.r.t. UPLC
Bharangi (Clerodendrum Serratum Linn) is one of ancient drug used in many preparations for treatment of many pathological conditions like Kasa, Shwasa, Jwara, Gulma, Aruchi, etc. That’s why there is need of pharmacognostical and phytochemical screening of different market samples of Bharangi (Clerodendrum Serratum Linn) with the help of UPLC study. Objectives: To undertake pharmacognostic and phytochemical screening of different market samples of roots of Bharangi (Clerodendrum Serratum Linn) and to compare the apigenin and Luteolin quantitatively in different market sample of root of Bharangi with the help of UPLC study. Materials and Methods: This was a laboratory-based study that included the analysis of different market samples of Bharangi (Clerodendrum Serratum Linn) in 3 phases, such as follows; a) Macroscopic and microscopic examinations with physio-chemical assessment involving the examination of ash value, pH water soluble extract, methanol - soluble external, acid insoluble ash and the extraction of volatile oil utilizing a clevenger apparatus. b) A qualitative phyto-chemical screening is conducted-demploying TLC method followed by phase 3 c) Which involves UPLC study. Results: The present showed that the market sample from Bengaluru had the highest quality of luteolin followed by Delhi and Rajasthan. All the three samples of Bharangi (Clerodendrum Serratum Linn) comprised both apigenin and luteolin with variations in both the quantity and this could be because of various factors such as soil properties, cultivation methods, environment, collection methods, extraction methods and age of plant. Conclusion: All the samples of Bharangi (Clerodendrum Serratum Linn) successfully fulfilled all the pharmacopoeia standards hence they are suitable for medicinal use.
Bharangi (clerodenrum serratum), Morphological, TLC, UPLC
Standardization and High-Performance Thin Layer Chromatographic Fingerprint Profiling of Manjishtha (Rubia Cordifolia L.) Roots
In Ayurvedic medicine, Manjishtha (Rubia cordifolia L.), a perennial climbing herb, is well recognized for its Raktashodhana (blood-cleansing) activity and its therapeutic use in Kuṣṭha (skin disorders), Vraṇa (wounds), and Prameha (urinary ailments). Its roots contain anthraquinones responsible for diverse pharmacological effects. Objective: To evaluate the pharmacognostic, physicochemical, and phytochemical properties of Manjishtha roots and develop a High-Performance Thin Layer Chromatographic (HPTLC) fingerprint for authentication and standardization. Methods: Collected roots were authenticated and were analysed as per Ayurvedic Pharmacopoeia standards through macroscopic, transverse and powder microscopic examinations. An analysis of physicochemical parameters such as moisture loss, ash values, solvent extractives, and pH was carried out. Alcoholic and aqueous extracts were screened for phytochemicals. High-Performance Thin Layer Chromatographic profiling was performed on silica gel GF 60 254 plates using Toluene: Ethyl Acetate: Formic Acid (7:3:1), scanned densitometrically at 254 and 366nm. Results: Roots were cylindrical, reddish-brown, and brittle, with microscopic features showing cork, cambium, phloem, xylem, and pith. Powder microscopy showed the presence of xylem elements, phloem fibres, lignified vessels and fibres. Physicochemical analysis indicated 0.39% foreign matter, 10% total ash, 24.53% alcohol-soluble extractives, 10.70% water-soluble extractives, and pH 6. Phytochemical screening confirmed the presence of alkaloids, flavonoids, saponins, tannins, glycosides, carbohydrates, phenol and steroids. The HPTLC chromatogram revealed 12 bands (Rf 0.006–0.958) at 254nm and 11 bands (Rf 0.006–0.976) at 366nm. Conclusion: The study establishes comprehensive pharmacognostic, physicochemical, and HPTLC data for Manjishtha (Rubia cordifolia L.) root, providing a valuable standard for identification and future research applications.
HPTLC fingerprinting, Manjishtha, Rubia cordifolia, Standardization
A Pharmaceutico-Analytical Study of Different Samples of Shilajit
Shilajit (Asphaltum punjabianum) is an important and widely used drug in Ayurveda. Shodhana of Shilajit was widely mentioned but the methods of analysis were restricted. The composition of Shilajit mainly depends on the variety of plants that are associated with the rocks. Even though the precise origin of Shilajit is unknown, its popularity is increasing in today's society. Despite being commonly used, there is a lack of data regarding the analytical profile of Shilajit. Aim: An effort has been made to purify both natural and market samples as per AFI and analyze both raw and Shudha Shilajit samples, study their composition, and create the data to help generate the standard parameters of the Shudha Shilajit which will help to reduce the research gap of Shilajit analysis.
Establishment of Standard Pharmaceutical Parameters for Mahasetu Rasa: A Classical Herbo-Mineral Formulation
Mahasetu Rasa, a classical Kupipakwa Rasayana preparation described in Rasa Kamdhenu, requires systematic purification (Shodhana) of Parada, Vanga, and Gandhaka, followed by Kajjali formation and heating in an Electric Muffle Furnace. The present study aimed to standardize its pharmaceutical preparation and evaluate the final product using modern analytical techniques. Pharmaceutical observations confirmed the successful detoxification of raw materials. Materials and Methods: Raw materials were purified by traditional methods: Parada with Churnodaka and garlic paste, Vanga via Samanya and Vishesh Shodhana in various media, and Gandhaka by repeated Dhalana with ghee and cow’s milk. Kajjali was prepared by amalgamation and trituration, and Mahasetu Rasa was heated upto 550°C in EMF. Results: Purified materials exhibited expected detoxification and physical changes. Kajjali showed classical properties. Pharmaceutical observations confirmed the successful detoxification of raw materials, yield was after Shodhana, Shuddha Vanga (Sn) - 90.8%, Shuddha Gandhaka (S) - 88.08%, Shuddha Parada (Hg) - 88.40%, Kajjali - 98.66%, Kupipakwa yielded MSR1 - 38.5%, MSR2 - 40.06, MSR3 - 39.1% final product after 26 hrs of heating and completion. Conclusion: The standardized method ensures reproducible preparation of Mahasetu Rasa through effective purification, controlled sublimation and fixation using EMF heating, thereby producing a safe and uniform product suitable for both clinical and research applications.
Kupipakwa Rasayana, Kajjali, Dhatu pishti, Vang, Tin, Parad, Mercury, Gandhaka, Shodhana
Pharmaceutical Preparation of Abhraka Bhasma: A Classical Approach Covering all Stages of Processing
Abhraka (mica) is essential in Rasashastra for its Rasayana properties and therapeutic applications. However, its raw form is unsuitable for direct medicinal use. To make it safe, effective, and easy for the body to absorb, it goes through special Ayurvedic processes. These include Shodhana, Dhanyabhraka, Marana, Amritikarana, and Lohitikarana. Materials and Methods: Raw Abhraka underwent sequential procedures Shodhana, Dhanyabhraka, Marana, Amritikarana, and Lohitikarana. Observations were recorded for changes in weight, texture, color, and classical parameters such as Nischandratva, Rekhapurnata, and Varitaratwa. Results: Shodhana caused 9.8% weight loss with improved brittleness and reduced impurities. Dhanyabhraka showed 23.83% weight loss, effective leaching, and pH reduction. Marana led to a 14.7% weight loss with color transition from blackish red to dull red. Amritikarana enhanced stability and reduced toxicity, while Lohitikarana imparted a red tinge and improved therapeutic potential. The final Bhasma was non-lustrous, floatable, and therapeutically active. Discussion: Stepwise processing confirmed the classical principles of Rasashastra, validating Ayurvedic principles of purification and incineration, ensuring safety, bioavailability, and Rasayana potential.
Abhraka, Shodhana, Dhanyabhraka, Marana, Amritikarana, Lohitikarana
A Comparative Pharmaco-Clinical Study of (Ficus Racemosa Linn.) and Indravaruni Phala Churna (Citrullus Colocynthis Schrad.) in the Management of Madhumeha (Type-2, Diabetes Mellitus)
One of the contemporary global health issues is diabetes mellitus. Because of their Pramehaghna (anti-diabetic) qualities and the numerous clinical trials in diabetes, Indravaruni Phala Churna are used to treat Madhumeha (diabetes mellitus). In order to compare the effects of Indravaruni Phala Churna, which are both manufactured in capsule form, on type 2 diabetes, the current study was conducted. Materials and methods: 60 patients with type 2 diabetes were treated with lukewarm water (1gm) and Indravaruni Phala Churna with lukewarm water (500mg) twice daily before meals for 60 days in this prospective, randomized, single-blind clinical experiment. Assessments were made of the alterations in hemoglobin, blood sugar, HbA1c, lipid profile, hepatic, renal, and clinical complaints. Results: and Indravaruni Phala Churna experienced a significant decrease in fasting blood glucose levels and a significant decrease in postprandial blood glucose levels following a 60-day treatment regimen. During the trial period, no adverse effects were reported. Conclusion: Compared to Ama Udumbara Phala Churna, Indravaruni Phala Churna is more successful, enhancing patients' quality of life while also providing significant glycemic control and having no negative side effects.
Diabetes Mellitus, Madhumeha, Ama Udumbara Phala churna, Indravaruni Phala churna
Successful Conception in Unexplained Primary Infertility Through Ayurveda
Primary infertility is defined as the inability to conceive after one year of unprotected intercourse, without any prior pregnancies. Unexplained infertility accounts for nearly 15–30% of cases, where no identifiable cause can be detected despite standard investigations. The current case study explores the Ayurvedic approach to manage unexplained primary infertility. Case Presentation: A 24-year-old nulligravida female presented with a 4-year history of primary infertility and scanty menstruation, despite normal findings in ovulation and her husband's semen analysis. Clinically, she had a BMI of 18.4 and exhibited signs of Artava Kshaya and Dhatu Kshaya, indicating Vata aggravation and nutritional insufficiency. Intervention and Management: A comprehensive Ayurvedic treatment protocol was initiated, including Samana and Shodhana therapies. Yoga Basti using Dashmoola was administered to pacify Vata and restore reproductive balance. Shatapushpa was used for its Artavajanana properties, along with nourishing Rasayana herbs like Ashwagandha, Shatavari, Vidarikanda, and Bala. Phala Ghrita was prescribed to stabilize the uterus and enhance fertility. Nutritional correction and Nidana Parivarjana were emphasized, alongside Beeja Sanskara and lifestyle guidance. Outcome: After the course of treatment, the patient’s menstrual flow normalized, BMI improved and hormonal balance was restored. A follicular study confirmed timely ovulation. Ultimately, the patient conceived, confirmed by a positive urine pregnancy test. Conclusion: This case demonstrates the effectiveness of individualized Ayurvedic management in addressing unexplained primary infertility. The approach, focusing on Vata Shamana, Dhatu Poshana led to successful conception. Ayurveda offers a promising alternative in cases where conventional diagnostics fail to identify a cause.
Infertility, Yoga Basti, Dhatu kshyajanya Vandhya, Beeja Sanskara
Hypothesizing the Mechanism of Action of Virechana in Neurological Diseases with Respect to the Gut-Brain Microbiota Axis
Panchakarma is an efficient and popular Ayurvedic treatment modality that helps eliminate various Doshic imbalances in the body to prevent and treat diseases. Its efficacy is being proven through multiple studies conducted across the globe; still, the mode of action of these therapies is to be understood far and wide. Virechana is one of the Panchakarmas that have an impact on the whole body to remove the Doshas that spread across the entire system. Due to this reason, it is considered best in the management of many disorders affecting different systems of the body, including the nervous system. The present review aimed at understanding the mechanism of action of Virechana with respect to the microbiota-gut-brain axis in neurological diseases. Virechana using Mridu and Snigdha medicines is mentioned for the management of Vatarogas. As Virechana is considered the primary treatment of pitta, its effect may be related to hormones and enzymes having neuroregulatory properties also. The microbiota-gut-brain axis plays an active role in the pathogenesis, management, and prevention of neurological diseases. Gastrointestinal complications like constipation are common in diseases affecting the nervous system, and they have shown a negative correlation with neurological recovery. Here comes the importance of Snigdha virechana or Mridu virechana mentioned in Vatavyadhi. Virechana can remove unfavorable bacterial colonization and is effective in correcting gut flora dysbiosis. Thus, the mechanism of action of Virechana in modifying the gut-brain axis and thereby facilitating neurologic recovery is understood. The present review sheds light on the Mechanism of action of Virechana with respect to the microbiota gut-brain axis in neurological disorders, which may be helpful for further research.
Virechana, Vatarogas, Microbiota-gut-Brain Axis, Neurological Diseases